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NSCLC ๋ฉด์—ญํ•ญ์•”์ œ ๋‚ด์„ฑ

๋ฌธํ—Œ ์ธํ…”๋ฆฌ์ „์Šค ยท Executive Brief

PMID 15๊ฑด ยท NSCLC ์•ต์ปค 1/3 ยท 2026-08-06

Executive Summary

๋น„์†Œ์„ธํฌํ์•”(NSCLC)์—์„œ ๋ฉด์—ญํ•ญ์•”์ œ(ICI)๋Š” ํ‘œ์ค€ ์น˜๋ฃŒ์ด๋‚˜, ์ดˆ๊ธฐ ๋ฐ˜์‘ ํ›„ ํš๋“ ๋‚ด์„ฑ(acquired resistance)์ด ํ”ํ•ฉ๋‹ˆ๋‹ค.

ํ…Œ๋งˆ์š”์•ฝ
ํ›„์„ฑ์œ ์ „ยท๋ผํ‹ธํ™”APOC2 lactylation ๋“ฑ ๋ฉด์—ญ์–ต์ œ ๋ฉ”์ปค๋‹ˆ์ฆ˜
์กฐํ•ฉ ์ „๋žตICI + TKI, ADC, ์ด์ค‘ ICI
๋ฐ”์ด์˜ค๋งˆ์ปคPD-L1, TMB, IFN-ฮณ ์‹œ๊ทธ๋‹ˆ์ฒ˜

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